Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Pravin M. Patel0
Date of Patent
May 27, 2008
Patent Application Number
10762652
Date Filed
January 22, 2004
Patent Primary Examiner
Patent abstract
Stabilized 17-substituted hydrocortisone containing compositions and methods of manufacture. Isomerization of the hydrocortisone component of topical steroid compositions is markedly reduced by introducing an omega-6. acid in the form of linoleic acid into the skin preparation. Preferably, the linoleic acid is added as a component of refined safflower oil. The omega-6 acid has been found to be an effective way of preventing the isomerization of hydrocortisone 17-butyrate into the undesirable isomer HC21-B.
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