Patent 7375227 was granted and assigned to Actelion Pharmaceuticals Ltd on May, 2008 by the United States Patent and Trademark Office.
The invention relates to novel 1-pyridin-4-yl urea derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.