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US Patent 7371826 Polypeptide variants with altered effector function

Patent 7371826 was granted and assigned to Genentech on May, 2008 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
Genentech
Genentech
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
73718260
Patent Inventor Names
Leonard Presta0
Date of Patent
May 13, 2008
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Patent Application Number
114297930
Date Filed
May 8, 2006
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Patent Citations Received
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US Patent 12134649 Anti-B7-H4 antibodies and immunoconjugates
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US Patent 12110339 ICOS ligand variant immunomodulatory proteins and uses thereof
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US Patent 12116414 Method of modifying isoelectric point of antibody via amino acid substitution in CDR
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US Patent 12122840 Method of modifying isoelectric point of antibody via amino acid substitution in CDR
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US Patent 12128101 Dosage and administration of anti-C5 antibodies for treatment of paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS)
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US Patent 11701357 Treatment of B cell cancers using a combination comprising Btk inhibitors
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US Patent 11753458 CTLA-4 variant immunomodulatory proteins and uses thereof
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US Patent 11760801 Anti-CEACAM antibodies and uses thereof
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Patent Primary Examiner
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Maher M. Haddad
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Patent abstract

The present invention concerns polypeptides comprising a variant Fc region. More particularly, the present invention concerns Fc region-containing polypeptides that have altered effector function as a consequence of one or more amino acid modifications in the Fc region thereof.

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