US Patent 7371370 Methods of using G-CSF analog compositions

Patent 7371370 was granted and assigned to Massachusetts Institute of Technology on May, 2008 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Massachusetts Institute of Technology

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

73713700

Patent Inventor Names

Casim A. Sarkar0

Douglas A. Lauffenburger0

Date of Patent

May 13, 2008

Patent Application Number

109100870

Date Filed

August 3, 2004

Patent Primary Examiner

‌

Prema Mertz

Patent abstract

The present invention relates to granulocyte colony stimulating factor (“G-CSF”) polypeptide analog compositions. The concept detailed herein provides methods for screening G-CSF analogs, designed with one or more substitutions to amino acids, and selecting analogs for use as G-CSF replacements or antagonists, and may be generalizable beyond G-CSF analogs as well. In addition, pharmaceutical compositions and methods of use are provided for analogs so selected.