Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Elisabeth Guillaume0
Jean-Charles Sanchez0
Catherine Gabrielle Zimmermann0
Denis Francois Hochstrasser0
Date of Patent
May 6, 2008
Patent Application Number
10238557
Date Filed
September 10, 2002
Patent Primary Examiner
Patent abstract
Heart and brain fatty acid binding proteins (H-FABP, B-FABP) are markers for TSEs, especially CJD. The invention provides a diagnostic assay for either of these markers, preferably by enzyme immunoassay using a specific antibody thereto. Since H-FABP is also a marker for acute myocardial infarction (AMI), to distinguish CJD from AMI requires an assay specific to AMI, e.g. using troponin-1 or CK-MB as a marker, also to be carried out.
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