Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Toshiki Taba0
Yasuaki Takakura0
Seiichi Hara0
Shunichi Suzuki0
Date of Patent
April 8, 2008
0Patent Application Number
116090180
Date Filed
December 11, 2006
0Patent Primary Examiner
Patent abstract
The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for producing optically active monatin, and an aldolase which can be used in these methods. As such, the present invention enables the synthesis of 4-(Indole-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid with high optical purity, which is useful as an intermediate in the synthesis of optically active monatin, from indole pyruvic acid and pyruvic acid (or oxaloacetic acid).
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