Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Jeremy J. W. Chen0
Pan-Chyr Yang0
Shuenn-Chen Yang0
Tse-Ming Hong0
Cheng-Wen Wu0
Jin-Yuan Shih0
Konan Peck0
Date of Patent
April 8, 2008
0Patent Application Number
101801980
Date Filed
June 25, 2002
0Patent Primary Examiner
Patent abstract
This invention is based on the discovery of an association of Collapsin Response Mediator Protein-1 (CRMP-1) with tumor metastasis. The level of CRMP-1 protein or mRNA can be used as an indicator of cellular invasiveness and of a test compound's ability to alter cellular invasiveness. The level of CRMP-1 protein can also be altered, e.g., to reduce invasiveness.
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