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US Patent 7345153 Compounds capable of inhibiting HIV-1 infection

Patent 7345153 was granted and assigned to Progenics Pharmaceuticals on March, 2008 by the United States Patent and Trademark Office.

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Patent
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Patent attributes

Current Assignee
Progenics Pharmaceuticals
Progenics Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
73451530
Patent Inventor Names
Graham P. Allaway0
Virginia M. Litwin0
Paul J. Maddon0
Date of Patent
March 18, 2008
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Patent Application Number
115443460
Date Filed
October 5, 2006
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Patent Primary Examiner
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Jeffrey S. Parkin
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Patent abstract

This invention provides an antibody capable of specifically inhibiting the fusion of an HIV-1 envelope glycoprotein+ cell with an appropriate CD4+ cell without cross reacting with the HIV-1 envelope glycoprotein or CD4 and capable of inhibiting infection by one or more strains of HIV-1. This antibody is then used to identify a molecule which is important for HIV infection. Different uses of the antibody and the molecule are described.

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