Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Michael Simons0
Youche Gao0
Date of Patent
March 18, 2008
0Patent Application Number
094260110
Date Filed
October 25, 1999
0Patent Primary Examiner
Patent abstract
The present invention provides both a method and means for regulating angiogenesis within living cells, tissues, and organs in-situ. The regulation is performed using native PR-39 peptide or one of its shorter-length homolog, for interaction with such proteasomes as one present in the cytoplasm of viable cells. The result of PR-39 peptide interaction with proteasomes is a decrease in the intracellular degradation of active peptides such as HIF-1α and a consequential stimulation of angiogenesis in-situ.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
