Collimator assemblies that include an inner combined collimator and an outer collimator are provided. The inner combined collimator includes a first portion having one or more slit apertures therein, and a second portion having one or more pinhole apertures therein. The outer collimator includes one or more septa spaced on a side of the first portion of the inner combined collimator. The slit apertures of the inner combined collimator and the septa of the outer collimator are arranged to define a plurality of apertures through the collimator assembly. Imaging systems that include the collimator assemblies and a detector assembly are also provided. The detector assembly may be configured to detect gamma rays emanating from a field of view that pass through apertures defined by the collimator assembly and to generate one or more signals in response to the detected gamma rays. Methods of imaging a field view using the collimating assembly are also provided.