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US Patent 7332277 Methods for detection of genetic disorders

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Is a
Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7332277
Patent Inventor Names
Ravinder S. Dhallan0
Date of Patent
February 19, 2008
Patent Application Number
10661165
Date Filed
September 11, 2003
Patent Citations Received
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US Patent 12116628 Rapid aneuploidy detection
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US Patent 12084720 Assessing graft suitability for transplantation
0
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US Patent 12110533 Stabilisation and isolation of extracellular nucleic acids
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US Patent 12110552 Methods for simultaneous amplification of target loci
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US Patent 12114654 Compositions and methods for stabilizing circulating tumor cells
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US Patent 11674176 Fetal aneuploidy detection by sequencing
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US Patent 11692225 Non-invasive fetal genetic screening by digital analysis
0
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US Patent 11697846 Detecting and classifying copy number variation
0
...
Patent Primary Examiner
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Ethan Whisenant
Patent abstract

The invention provides a method useful for detection of genetic disorders. The method comprises determining the sequence of alleles of a locus of interest, and quantitating a ratio for the alleles at the locus of interest, wherein the ratio indicates the presence or absence of a chromosomal abnormality. The present invention also provides a non-invasive method for the detection of chromosomal abnormalities in a fetus. The invention is especially useful as a non-invasive method for determining the sequence of fetal DNA. The invention further provides methods of isolation of free DNA from a sample.

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