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US Patent 7316801 High throughput microfluidic systems and methods

Patent 7316801 was granted and assigned to Caliper Life Sciences on January, 2008 by the United States Patent and Trademark Office.

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Is a
Patent
Patent

Patent attributes

Current Assignee
‌
Caliper Life Sciences
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7316801
Patent Inventor Names
Steven A. Sundberg0
Andrew W. Toth0
Calvin Y. H. Chow0
J. Wallace Parce0
Jeffrey A. Wolk0
Joseph E. Kercso0
Date of Patent
January 8, 2008
Patent Application Number
10244227
Date Filed
September 16, 2002
Patent Citations Received
‌
US Patent 12105023 Multi-well plate readers and methods of their use
0
Patent Primary Examiner
‌
Brian R. Gordon
Patent abstract

The invention provides improved systems, devices, and methods for analyzing a large number of sample compounds contained in standard multi-well microtiter plates or other array structures. The multi-well plates travel along a conveyor system to a test station having a microfluidic device. At the test station, each plate is removed from the conveyor and the wells of the multi-well plate are sequentially aligned with an input port of the microfluidic device. After at least a portion of each sample has been input into the microfluidic channel system, the plate is returned to the conveyor system. Pre and/or post testing stations may be disposed along the conveyor system, and the use of an X-Y-Z robotic arm and novel plate support bracket allows each of the samples in the wells to be input into the microfluidic network through a probe affixed to a microfluidic chip. A clamshell structure having a hinged lid can releasably support the chip while providing and/or accommodating the electrical, optical, structural, and other interface connections between the microfluidic device and the surrounding system.

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