Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Fawn Coles0
Lars Karlsson0
Anne M. Fourie0
Date of Patent
December 25, 2007
0Patent Application Number
110127970
Date Filed
December 15, 2004
0Patent Primary Examiner
Patent abstract
The present invention describes synthetic peptide substrates of the metalloproteases, aggrecanase-1 and/or -2 suitable for assays of enzyme activity. The invention also describes methods using these peptides to discover pharmaceutical agents that modulate these proteases.
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