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US Patent 7303879 Determination of SNP allelic frequencies using temperature gradient electrophoresis

Patent 7303879 was granted and assigned to Applera on December, 2007 by the United States Patent and Trademark Office.

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Patent abstract

A method for determining a frequency of single nucleotide polymorphism (SNP) within genomic DNA includes providing genomic DNA of each of a plurality of different organisms. The genomic DNA of each organism includes first and second portions, e.g., first and second strands. First and second amplicons are prepared from the genomic DNA of each organism. The first amplicon corresponds to the first portion of the genomic DNA and the second amplicon corresponds to the second portion of the genomic DNA.

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