Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Gilles Piquet0
Luca Barbero0
Monica Gatti0
Silvio Traversa0
Date of Patent
August 14, 2007
0Patent Application Number
103983970
Date Filed
October 3, 2001
0Patent Primary Examiner
Patent abstract
A method is described for a method for the regioselective liquid-phase pegylation of GRF, which increases the yield of the GRF-PEG conjugate having 1 PEG molecule covalently bound to the e-amino group of Lys12. This method is characterized in that the reaction is carried out in a structuring solvent, such as trifluorethanol.
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