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US Patent 7256020 Methods and compositions for detecting target sequences

Patent 7256020 was granted and assigned to Third Wave Technologies on August, 2007 by the United States Patent and Trademark Office.

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Current Assignee
Third Wave Technologies
Third Wave Technologies
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
72560200
Patent Inventor Names
Victor Lyamichev0
Bruce P. Neri0
Jeff Hall0
Andrew Lukowiak0
Date of Patent
August 14, 2007
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Patent Application Number
103568610
Date Filed
February 3, 2003
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Patent Citations Received
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US Patent 12109223 Polymer nanoparticle and DNA nanostructure compositions and methods for non-viral delivery
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0
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US Patent 12060620 Multiplexed KRAS mutation detection assay
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Patent Primary Examiner
Young J. Kim
Young J. Kim
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Patent abstract

The present invention relates to compositions and methods for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. The present invention relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. For example, in some embodiments, a 5′ nuclease activity from any of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.

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