Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
David McKenney0
Gerald B. Pier0
Julia Y. Wang0
Date of Patent
August 7, 2007
Patent Application Number
09771003
Date Filed
January 26, 2001
Patent Primary Examiner
Patent abstract
The invention relates to compositions of the capsular polysaccharide/adhesin (PS/A) of staphylococci. The PS/A may be isolated or synthesized and includes various modifications to the structure of native PS/A based on the chemical characterization of PS/A. The invention also relates to the use of the PS/A as a vaccine for inducing active immunity to infections caused by Staphylococcus aureus, S. epidermidis, other related coagulase-negative staphylococci and organisms carrying the ica (intracellular adhesin) locus, and to the use of antibodies directed to PS/A for inducing passive immunity to the same class of infections.
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