Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Donald W. Kufe0
Ralph R. Weichselbaum0
Date of Patent
July 24, 2007
0Patent Application Number
102447050
Date Filed
September 16, 2002
0Patent Primary Examiner
Patent abstract
The present invention provides for improved vectors for use in gene therapy. Utilizing the cancer specific DF3/MUC1 promoter to drive a replication essential gene, vectors are made conditionally replication-competent, permitting wider infection and expression of tumor cells. In addition, therapeutic genes and adjunct therapies further increase anti-tumor efficacy.
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