Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Reuven Agami0
Thijn Brummelkamp0
Date of Patent
July 10, 2007
0Patent Application Number
103241840
Date Filed
December 19, 2002
0Patent Primary Examiner
Patent abstract
The present invention provides a polynucleotide comprising a RNA polymerase III promoter, a region encoding a siRNA, and a transcriptional termination element comprising five consecutive thymine residues. The invention also provides for vectors, cells and non-human transgenic animal comprising the polynucleotides of the invention as well as their use in medicaments for various conditions.
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