Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ruiping Liu0
Allen Hopper0
Ashok Tehim0
Erik Kuester0
Hans-Jurgen Ernst Hess0
Mike De Vivo0
Date of Patent
June 26, 2007
0Patent Application Number
102707240
Date Filed
October 16, 2002
0Patent Primary Examiner
Patent abstract
Selective PDE4 inhibition is achieved by 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds like rolipram and show selectivity with regard to inhibition of other classes of PDEs. The compounds of the present invention are of formula I:wherein R1, R2, and R3 are as defined herein.
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