Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Qiong Cheng0
Pamela L. Sharpe0
Luan Tao0
Natalia Sedkova0
Melissa D. Bosak0
Date of Patent
June 19, 2007
Patent Application Number
10997844
Date Filed
November 24, 2004
Patent Primary Examiner
Patent abstract
Methanotrophic bacterial strains are provided that have been optimized for the production of carotenoid compounds through the down-regulation of one or more of the crtN1, ald, crtN2 and crtN3 genes of the carotenoid biosynthetic pathway. The resulting strains lack pigmented C30 carotenoid compounds, and show an increase in the production of C40 carotenoids. The use of the optimized host strains for the production of the C40 carotenoids canthaxanthin and astaxanthin is also described.
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