Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
David N. Krag0
Lyn Oligino0
Stephanie C. Pero0
Date of Patent
June 12, 2007
0Patent Application Number
100138150
Date Filed
November 5, 2001
0Patent Primary Examiner
Patent abstract
The invention provides methods and compositions for treating subjects using Grb7 antagonists. Specifically disclosed are Grb7 antagonists that bind selectively to Grb7 and interfere with the ability of Grb7 to bind to its native ligands. These compositions are useful in the prevention and treatment of disorders characterized by abnormal interaction of Grb7 with its native ligands (e.g., ErbB2).
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