Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
June 12, 2007
Patent Application Number
09454851
Date Filed
December 7, 1999
Patent Citations Received
Patent Primary Examiner
Patent abstract
T cell activation in response to antigen is increased by the administration of binding agents that block CTLA-4 signaling. When CTLA-4 signaling is thus blocked, the T cell response to antigen is released from inhibition. Such an enhanced response is useful for the treatment of tumors, chronic viral infections, and as an adjuvant during immunization.
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