Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ken White0
Michael Econs0
Thomas Meitinger0
Tim Matthias Strom0
Date of Patent
May 29, 2007
0Patent Application Number
099019380
Date Filed
July 10, 2001
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention relates to novel nucleic acids encoding a fibroblast growth factor-23(FGF23) and proteins encoded thereby, mutations in which are associated with autosomal dominant rickets (ADHR). The invention further relates to methods of diagnosing and treating hypophosphatemic and hyperphosphatemic disorders comprising inhibiting or stimulating, respectively, the biological activity of FGF23 in a patient. The invention also relates to methods of treating osteoporosis, dermatomyositis, and coronary artery disease comprising stimulating the biological activity of FGF23 in a patient.
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