Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yuhong Zhou0
Qu Dong0
Roy C. Levitt0
W. Lee Maloy0
Jamila Louahed0
Kenneth J. Holroyd0
Mike McLane0
Nicholas C. Nicolaides0
Date of Patent
May 1, 2007
0Patent Application Number
107724370
Date Filed
February 6, 2004
0Patent Primary Examiner
Patent abstract
A new gene in the calcium-activated chloride channel family has been discovered that is induced by IL-9, thereby providing a therapeutic target in IL-9 mediated development of atopic allergy, asthma-related disorders and cystic fibrosis. A method for the identification and use of small molecule inhibitors of this gene and its products to treat these disorders has also been discovered. The invention also includes a method for diagnosing susceptibility to, and assessing treatment of atopic allergy, asthma-related disorders by measuring the level of gene expression in biologic samples using antibody specific for this protein.
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