Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Lihong Guo0
Michael David Bentley0
Xiaoming Shen0
Xuan Zhao0
Date of Patent
April 17, 2007
0Patent Application Number
112645460
Date Filed
November 1, 2005
0Patent Primary Examiner
Patent abstract
The invention provides a sterically hindered polymer that comprises a water-soluble and non-peptidic polymer backbone having at least one terminus covalently bonded to an alkanoic acid or alkanoic acid derivative, wherein the carbon adjacent to the carbonyl group of the acid or acid derivative group has an alkyl or aryl group pendent thereto. The steric effects of the alkyl or aryl group allow greater control of the hydrolytic stability of polymer derivatives. The polymer backbone may be poly(ethylene glycol).
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