A biologically resorbable nerve guide rail with a microporous guide tube of polymers of hydroxycarboxylic acids, where the porosity allows a metabolism through the tube wall, but prevents the passage of cells, and optionally several monofilaments of polymers of hydroxycarboxylic acids located in the guide tube, is characterized in that the inner surface of the tube and/or the surface of the monofilaments have an orientation aid for longitudinally oriented colonization with Schwann's cells.