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US Patent 7198784 Retroviral vectors

Patent 7198784 was granted and assigned to Oxford Biomedica (UK) Limited on April, 2007 by the United States Patent and Trademark Office.

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Current Assignee
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Oxford Biomedica (UK) Limited
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
71987840
Patent Inventor Names
Susan Mary Kingsman0
Kyriacos Mitrophanous0
Narry Kim0
Alan John Kingsman0
Date of Patent
April 3, 2007
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Patent Application Number
106617610
Date Filed
September 11, 2003
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Patent Citations Received
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US Patent 11965892 HLA-based methods and compositions and uses thereof
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US Patent 11834718 Compositions and methods for diagnosing, evaluating and treating cancer by means of the DNA methylation status
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US Patent 11939637 Molecular biomarkers for cancer immunotherapy
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Patent Primary Examiner
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Richard Schnizer
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Patent abstract

Retroviral vector production systems for producing lentivirus-based vector particles which are capable of infecting and transducing non-dividing target cells, wherein one or more of the auxiliary genes such as vpr, vif, tat, and nef in the case of HIV-1 are absent from the system. The systems and resulting retrovirus vector particles have improved safety over existing systems and vectors.

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