US Patent 7195871 Methods and compositions for detecting target sequences

Patent 7195871 was granted and assigned to Third Wave Technologies on March, 2007 by the United States Patent and Trademark Office.

Overview Structured Data Issues Contributors Activity

Is a

Patent

Patent attributes

Current Assignee

Third Wave Technologies

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

71958710

Patent Inventor Names

Bruce P. Neri0

Victor Lyamichev0

Andrew A. Lukowiak0

Jeff Hall0

Date of Patent

March 27, 2007

Patent Application Number

102903860

Date Filed

November 7, 2002

Patent Citations Received

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US Patent 12060620 Multiplexed KRAS mutation detection assay

Patent Primary Examiner

Young J. Kim

Patent abstract

The present invention relates to compositions and methods for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. The present invention relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. For example, in some embodiments, a 5′ nuclease activity from any of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.