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US Patent 7189741 Indolylpiperidine derivatives as antihistaminic and antiallergic agents

Patent 7189741 was granted and assigned to Almirall on March, 2007 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
Almirall
Almirall
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
71897410
Patent Inventor Names
Silvia Fonquerna Pou0
Carles Puig Duran0
Lidia Soca Pueyo0
Lluis Pages Santacana0
Date of Patent
March 13, 2007
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Patent Application Number
104156930
Date Filed
October 26, 2001
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Patent Primary Examiner
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Celia Chang
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Patent abstract

The invention relates to indolyl piperidinyl derivatives of formula (I) wherein: A1 represents an alkylene, alkyleneoxy, alkylenethio, alkanoylene or hydroxyalkylene group; A2 represents an alkylene, alkyleneoxy, alkylenethio, alkanoylene or an alkyleneoxyalkylene group; W1 represents a phenylene, furanylene or pyridinylene group which is unsubstituted or substituted by one or more halogen atoms, alkoxy groups and/or alkyl groups; W2 represents a 3–10 membered monocyclic or bicyclic group containing from 1 to 3 heteroatoms said group being unsubstituted or substituted by one or more halogen atoms, alkyl groups, alkoxy groups and/or oxo groups; R1 represents a hydrogen or halogen atom or an alkyl, alkoxy or methylamino group; and R2 represents a carboxyl group; and pharmaceutically acceptable salts thereof; to processes for their preparation; to pharmaceutical compositions containing them; and to their medical use as antihistaminic and antiallergic agents.

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