US Patent 7189391 Method of

Patent 7189391 was granted and assigned to Laval University on March, 2007 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Laval University

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7189391

Date of Patent

March 13, 2007

Patent Application Number

10105815

Date Filed

March 21, 2002

Patent Primary Examiner

‌

Brian Whiteman

Patent abstract

Methods of pre-treating healthy donor's myoblast cultures with growth or trophic factors on transplantation into subjects suffering from myopathic conditions such as muscular dystrophy. Compositions comprising myoblasts and fusion-promoting metalloproteases can be transplanted. Alternatively, myoblasts can be transplanted along with an agent inducing the expression of a fusion-promoting metalloprotease, or a composition comprising genetically-modified myoblasts capable of expressing a fusion-promoting metalloprotease can be transplanted.