US Patent 7186681 Methods of modulating cell migration using galectin-3

Patent 7186681 was granted and assigned to La Jolla Institute for Allergy and Immunology on March, 2007 by the United States Patent and Trademark Office.

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Patent Inventor Names

Daniel K. Hsu0

Fu-Tong Liu0

Hideki Sano0

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Patent abstract

The present invention relates to methods of modulating cell migration, particularly, monocyte, neutrophil or macrophage migration, using galectin-3, galectin-3 binding polypeptide, or galectin-3 receptor binding polypeptide. Specifically provided are methods for increasing cell migration to sites of inflammation, infection or a tumor. Also provided are methods for identifying agents that modulate galectin-3 mediated migration, compositions containing galectin-3 or a functional subsequence thereof, and microfabricated devices that deliver galectin-3 or functional galectin-3 subsequences.

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https://pdfpiw.uspto.gov/.piw?Docid=071866810

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