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US Patent 7179630 Thermostable proteases

Patent 7179630 was granted and assigned to Novozymes A/S on February, 2007 by the United States Patent and Trademark Office.

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Current Assignee
Novozymes A/S
Novozymes A/S
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7179630
Patent Inventor Names
Carsten Andersen1
Morten Fischer1
Carsten Sjoeholm1
Soeren Flensted Lassen1
Peter Rahbek Oestergaard1
Date of Patent
February 20, 2007
Patent Application Number
10873593
Date Filed
June 21, 2004
Patent Primary Examiner
‌
Sheridan Swope
Patent abstract

The present invention relates to thermostable proteases having an amino acid sequence which homologous to the amino acid sequence of proteases derived from Nocardiopsis, and the production thereof by wild-type and recombinant host cells including transgenic plants and non-human transgenic animals. The proteases are effective in animal feed, in particular fish feed, and detergents. The proteases are capable of degrading the soybean Bowman-Birk inhibitor, and other antinutritional factors such as soybean agglutinin and the Kunitz trypsin inhibitor, as well as the isolated soy storage proteins glycinin and beta-conglycinin. Characteristic structural features of relevance for the thermostability of these proteases of peptidase family S2A or S1E are disclosed.

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