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US Patent 7179616 Method for detecting phosphatidylserine on the surface of cells

Patent 7179616 was granted and assigned to University of Notre Dame on February, 2007 by the United States Patent and Trademark Office.

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Patent
Patent
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Current Assignee
University of Notre Dame
University of Notre Dame
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
71796160
Patent Inventor Names
Bradley D. Smith0
Date of Patent
February 20, 2007
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Patent Application Number
106562370
Date Filed
September 8, 2003
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Patent Primary Examiner
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Mary E. Ceperley
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Patent abstract

The present invention relates generally to a method and compound for sensing the presence of anionic phospholipids, especially phosphatidylserine, on the surface of vesicles and cells. Upon introducing a compound having the structure below to a sample of cells or vesicles, the compound binds to anionic phopholipids on the surface of cells or vesicles and the presence of the compound is detected reflecting the presence of anionic phospholipids in the sample

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