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US Patent 7157557 Increased recovery of active proteins

Patent 7157557 was granted and assigned to Immunex on January, 2007 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
Immunex
Immunex
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
71575570
Patent Inventor Names
Rebecca E. McCoy0
Helmut M. Sassenfeld0
Richard L. Remmele, Jr.0
Date of Patent
January 2, 2007
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Patent Application Number
100804710
Date Filed
February 22, 2002
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Patent Citations Received
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US Patent 11969456 Lipoprotein complexes and manufacturing and uses thereof
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US Patent 11998587 Lipoprotein complexes and manufacturing and uses thereof
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Patent Primary Examiner
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Eileen B. O'Hara
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Patent abstract

The invention provides methods of increasing yields of desired conformation of proteins. In particular embodiments, the invention includes contacting preparations of a recombinant protein with a reduction/oxidation coupling reagent for a time sufficient to increase the relative proportion of a desired configurational isomer.

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