Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kevin M. Klucher0
Wayne R. Kindsvogel0
Katherine E. Henderson0
Pallavur V. Sivakumar0
Date of Patent
November 14, 2006
Patent Application Number
10691923
Date Filed
October 23, 2003
Patent Citations Received
Patent Primary Examiner
Patent abstract
IL-28A, IL-28B, IL-29, and certain mutants thereof have been shown to have antiviral activity on a spectrum of viral species. Of particular interest is the antiviral activity demonstrated on viruses that infect liver, such as hepatitis B virus and hepatitis C virus. In addition, IL-28A, IL-28B, IL-29, and mutants thereof do not exhibit some of the antiproliferative activity on hematopoietic cells that is observed with interferon treatment. Without the immunosuppressive effects accompanying interferon treatment, IL-28A, IL-28B, and IL-29 will be useful in treating immunocompromised patients for viral infections.
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