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US Patent 7112671 Non-symmetric tripyrranes in the synthesis of novel macrocycles

Patent 7112671 was granted and assigned to Pharmacyclics on September, 2006 by the United States Patent and Trademark Office.

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Patent

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Current Assignee
Pharmacyclics
Pharmacyclics
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7112671
Patent Inventor Names
Joshua Galanter0
Tarak D. Mody0
Date of Patent
September 26, 2006
Patent Application Number
10363401
Date Filed
August 28, 2001
Patent Primary Examiner
‌
James O. Wilson
Patent abstract

The present invention provides certain non-symmetric tripyrranes; that is, tripyrranes that do not contain a mirror plane of symmetry perpendicular to the plane containing the tripyrrane. Further, the invention includes texaphyrin compounds and sapphyrin compounds, as well as other polypyrrolic macrocycles, prepared using tripyrranes of Formula I as a precursor. These macrocycles are characterized by a tripyrrolic portion of the macrocyclic ring having substituents that cause the heterocycle to lack a plane of symmetry perpendicular to the plane of the macrocycle.

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