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US Patent 7110808 Method of optimizing radiosurgery and radiotherapy with metalloporphyrins

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Patent
Patent

Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7110808
Patent Inventor Names
Edwin L. Adair0
Date of Patent
September 19, 2006
Patent Application Number
10836454
Date Filed
April 30, 2004
Patent Citations Received
‌
US Patent 12023523 Systems and methods for fault detection in emission-guided radiotherapy
0
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US Patent 11801398 Beam station treatment planning and radiation delivery methods
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US Patent 11878185 High bandwidth binary multi-leaf collimator design
0
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US Patent 11904184 Radiation therapy systems and methods with tumor tracking
0
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US Patent 11975220 System for emission-guided high-energy photon delivery
0
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US Patent 11675097 Methods for PET detector afterglow management
0
Patent Primary Examiner
‌
Ralph Gitomer
Patent abstract

An apparatus and method for subsequent optimization of radiosurgery and radiotherapy is provided. The invention includes administering a metalloporphyrin to the patient, and then creating a 3-dimensional mapping of tissue through use of PET or SPECT. Malignant and pre-malignant tissue has an affinity for the metalloporphyrin. During treatment, real-time images are also provided which are compared to the previous 3-dimensional mapping. Creation of the real-time images is also achieved through PET or SPECT wherein a metalloporphyrin is administered to the patient. Total administration of radiation is calculated by summing radiation from the metalloporphyrins and from the radiosurgery/radiotherapy. The amount of radiation delivered by the metalloporphyrins and by the radiosurgery/radiotherapy are adjustable based on a patient's response to the dual delivery.

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