Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Date of Patent
September 5, 2006
Patent Application Number
10112416
Date Filed
March 29, 2002
Patent Citations Received
0
Patent Primary Examiner
Patent abstract
The invention provides methods of controlling pH variations during chromatography. In particular embodiments, the invention includes equilibrating and eluting proteins from chromatography resins have a solid phase that possesses a charged functional group on its backbone under controlled conditions of osmolarity and pH. The invention is particularly useful in the purification of proteins that are sensitive to pH transitions such as, for example, the IL-1 Receptor type II protein.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
