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US Patent 7101467 Mixed mode microfluidic systems

Patent 7101467 was granted and assigned to Caliper Life Sciences on September, 2006 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
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Caliper Life Sciences
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
71014670
Patent Inventor Names
Michael A. Spaid0
Date of Patent
September 5, 2006
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Patent Application Number
107449150
Date Filed
December 22, 2003
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Patent Citations Received
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US Patent 12128405 Microfluidic valve and method of making same
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US Patent 11788127 Scanning real-time microfluidic thermocycler and methods for synchronized thermocycling and scanning optical detection
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US Patent 11959126 Microfluidic system for amplifying and detecting polynucleotides in parallel
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US Patent D1029291 Single piece reagent holder
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US Patent 12128402 Microfluidic cartridge
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Patent Primary Examiner
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Alex Noguerola
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Patent abstract

Methods and systems that employ hybrid fluid flow profiles for optimized movement of materials through channel networks. These systems employ hybrid pressure-based and electrokinetic based flow systems for moving materials through interconnected channel networks while maintaining interconnection among the various channel segments. In particular, the invention is generally directed to channel networks where flow in a first channel segment is driven by pressure flow with its consequent parabolic flow profile, while flow in an interconnected channel segment is dominated by electrokinetic flow with its consequent plug flow profile. The invention also provides channel networks wherein fluid flow in channel segments is driven by both pressure and electric field and the multiple species contained in a fluid plug are separated (and can be concentrated) by altering the applied pressure and electric fields in the various channel segments of the channel networks.

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