A process for producing a medical guide wire comprising a step S2, S5 for inserting the core wire and coil into a tubular die having the desired curved form, a step S3, S6 for heat-treating the core wire and coil in the die, a step 7 for removing oxide skin or films from the heat-treated core wire, a step S8 for assembling the obtained coil to the core wire, a step S9 for brazing or soldering an end of the coil to the core wire, a step S10 for grinding or sandering the obtained guide wire, and then a step for washing the guide wire.