Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Sylvia Krobitsch0
Susan Lindquist0
Tiago Fleming Outeiro0
Date of Patent
May 16, 2006
0Patent Application Number
100775840
Date Filed
February 15, 2002
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Screening methods for identifying substances that provide therapeutic value for various diseases associated with protein misfolding are provided. Genetic and chemical screening methods are provided using a yeast system. The methods of the invention provide a rapid and cost-effective method to screen for compounds that prevent protein misfolding and/or protein fibril formation and/or protein aggregation which includes numerous neurodegenerative diseases including Parkinson's disease, Alzheimer's disease, Huntington's disease as well as non-neuronal diseases such as type 2 diabetes.
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