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US Patent 7037698 Pyrroloquinoline quinone-dependent glucose dehydrogenase

Patent 7037698 was granted and assigned to Amano Enzyme Inc. on May, 2006 by the United States Patent and Trademark Office.

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Current Assignee
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Amano Enzyme Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
70376980
Patent Inventor Names
Norio Hamamatsu0
Akitoshi Suzumura0
Date of Patent
May 2, 2006
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Patent Application Number
108478670
Date Filed
May 19, 2004
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Patent Primary Examiner
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Rebecca E. Prouty
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Patent abstract

A modified pyrroloquinoline quinone-dependent glucose dehydrogenase having a low reactivity with respect to maltose, galactose, etc. is provided. A modified pyrroloquinoline quinone-dependent glucose dehydrogenase including an amino acid sequence in which one or more amino acids in a region corresponding to a first region consisting of amino acids at positions 326 to 354 in pyrroloquinoline quinone-dependent glucose dehydrogenase derived from Acinetobacter calcoaceticus are substituted as compared with an amino acid sequence of the corresponding wild-type enzyme.

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