Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yoshihiko Okaichi0
Yasuhiro Yamada0
Akihiro Yamamoto0
Hisashi Miyamoto0
Michiaki Tominaga0
Norihiro Fukuyama0
Date of Patent
April 11, 2006
0Patent Application Number
104889510
Date Filed
September 9, 2003
0Patent Primary Examiner
Patent abstract
The present invention provides a process for producing cilostazol [I] in a high yield and a high purity, by reacting a carbostyril derivative [II] with a tetrazole derivative [III] in the presence of an inorganic basic compound in a solvent of water, wherein water is used in an amount of 3 to 7-fold weight to that of the carbostyril derivative [II] and the inorganic basic compound is used in an amount of 1 to 6 mol per mol of the carbostyril derivative [II]. The process of the present invention is the improved and environment-friendly process for producing cilostazol being useful for pharmaceuticals
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