US Patent 6998850 Systems and methods for measuring picoampere current levels

In one embodiment, a circuit measures picoampere current levels. The circuit comprises: an operational-amplifier that has differential inputs and differential outputs; a switching structure that switchably couples an input line to one of the differential inputs in response signals from a timing circuit; a first integrating capacitor coupled to one of the differential inputs and to one of the differential outputs; a second integrating capacitor coupled to the other of the differential inputs; and a charge injection compensation structure that selectively injects charge into the input line and removes charge from the input line in response to signals from the timing circuit.