Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
David E. Benson0
David W. Conrad0
Homme W. Hellinga0
Date of Patent
December 20, 2005
0Patent Application Number
102292860
Date Filed
August 28, 2002
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention relates, in general, to biosensors and, in particular, to bioelectronic sensors comprising a macromolecule immobilized on an electrode surface so that a redox cofactor that is site-specifically attached to the surface of the macromolecule is between the macromolecule and electrode surface ligand-mediated conformational changes alter the geometry of interaction between the redox cofactor and the electrode surface resulting in a change in electronic coupling between the cofactor and electrode.
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