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US Patent 6977161 Solid support assay systems and methods utilizing non-standard bases

Patent 6977161 was granted and assigned to ERAGEN BIOSCIENCES, INC. on December, 2005 by the United States Patent and Trademark Office.

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Patent
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Current Assignee
ERAGEN BIOSCIENCES, INC.
ERAGEN BIOSCIENCES, INC.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
69771610
Patent Inventor Names
Eric B. Roesch0
James R. Prudent0
Jerod L. Ptacin0
Jennifer K. Grenier0
Christopher B. Sherrill0
Christopher W. Scherrer0
Craig S. Richmond0
David J. Marshall0
Date of Patent
December 20, 2005
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Patent Application Number
099776150
Date Filed
October 15, 2001
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Patent Primary Examiner
‌
Kenneth R Horlick
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Patent abstract

Solid support assays using non-standard bases are described. A capture oligonucleotide comprising a molecular recognition sequence is attached to a solid support and hybridized with a target oligonucleotide. In some instances, the molecular recognition sequence includes one or more non-standard bases and hybridizes to a complementary tagging sequence of the target oligonucleotide. In other instances, incorporation of a non-standard base (e.g., via PCR or ligation) is used in the assay.

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