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US Patent 6949537 PI-3 kinase inhibitor prodrugs

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Patent Applicant

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Patent Jurisdiction

United States Patent and Trademark Office

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Patent Number

Patent Inventor Names

Mary Patterson0

Donald L. Durden0

Jingdong Su0

Joseph R. Garlich0

Robert G. Suhr0

Date of Patent

September 27, 2005

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Patent Application Number

108181450

Date Filed

April 5, 2004

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Patent Citations Received

US Patent 11932624 MDM2 degraders and uses thereof

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US Patent 11932635 CRBN ligands and uses thereof

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US Patent 12006329 Protein degraders and uses thereof

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US Patent 12077555 STAT degraders and uses thereof

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US Patent 12091411 IRAK degraders and uses thereof

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Patent Primary Examiner

Cecilia J. Tsang

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Patent abstract

The invention provides novel prodrugs of inhibitors of PI-3 kinase. The novel compounds are LY294002 and analogs thereof comprising a reversibly quaternized amine.

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