Is a
Patent attributes
Patent Applicant
0
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Maralee McVean0
Arthur Yeung0
Bruce H. Devens0
Kevin J. Kennedy0
Mark R. Burns0
Date of Patent
July 19, 2005
0Patent Application Number
104437430
Date Filed
May 23, 2003
0Patent Primary Examiner
Patent abstract
The synthesis and use of a novel class of tumor necrosis factor (TNFα) inhibitors and immunomodulators are provided. These compounds have pharmacological applications as well as uses in assays relating to TNFα and other involved cytokines. As pharmaceuticals, these compounds are used to treat inflammatory, infectious, autoimmune or other proliferative diseases and conditions related to the unwanted presence or activity of TNFα and/or one or more other involved cytokines, alone or in combination with other agents. Examples of compounds of the present invention are those having the structures as shown below:
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