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US Patent 6919172 Preservation and storage medium for biological materials

Patent 6919172 was granted and assigned to Wisconsin Alumni Research Foundation on July, 2005 by the United States Patent and Trademark Office.

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Contents

Is a
Patent
Patent
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Patent attributes

Patent Applicant
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Current Assignee
Wisconsin Alumni Research Foundation
Wisconsin Alumni Research Foundation
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
69191720
Patent Inventor Names
Juan DePablo0
Danforth Miller0
Horacio Corti0
Paul Conrad0
Date of Patent
July 19, 2005
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Patent Application Number
106570170
Date Filed
September 5, 2003
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Patent Citations Received
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US Patent 12115280 Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
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US Patent 11911256 Dry prosthetic heart valve packaging system
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US Patent 12023416 Collagen fibers and articles formed therefrom
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US Patent 12023417 Method for pre-stretching implantable biocompatible materials, and materials, and devices produced thereby
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US Patent 12121022 Stabilization of thrombocytes at ambient temperatures
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US Patent 12089588 Reduction of erythrocyte sedimentation rate
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Patent Primary Examiner
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Jon Weber
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Patent abstract

A protectant mixture for use in preserving biological materials comprising (1) at least one polyhydroxy compound, where the total amount of polyhydroxy compound in the mixture is from about 5% to about 60% by weight of the mixture where the mixture is an aqueous solution and is from about 10% to about 95% where the mixture is in solid form, and (2) phosphate ions, where the total amount of phosphate ions in the mixture is such that the molar ratio of phosphate ions to hydroxy groups in the polyhydroxy compound is from about 0.025 to about 0.625; a preservation medium comprising (1) a biological material, (2) at least one polyhydroxy compound, where the total amount of polyhydroxy compound in the medium is from about 5% to about 60% by weight of the medium, and (3) phosphate ions, where the total amount of phosphate ions in the mixture is such that the molar ratio of phosphate ions to hydroxy groups in the polyhydroxy compound is from about 0.025 to about 0.625; methods of preserving the preservation medium; and the resulting preserved biological material composition.

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